Monday, August 11, 2014

Patented Tobacco Plant Genetically Engineered to Produce Antibodies Against Ebola gets Boost to Treat Dr. Kent Brantly and Nancy Writebol


Dr. Kent Brantly and Nancy Writebol, infected with Ebola, are being treated at Emory University hospital with an experimental cocktail of antibodies which target the deadly virus.  But these antibodies are not just any antibodies; they were synthesized and harvested from tobacco plants that scientists genetically engineered to produce antibodies against Ebola.


A team of scientists has worked for around twenty years on uses of plant-based therapeutics for the prevention and treatment of disease.  In August of 2013, U.S. Patent No. 8,513,397 ("Mason, et al.") entitled, DNA replicon system for high-level rapid production of vaccines and monoclonal antibody therapeutics in plants, issued on the technology which was initially filed as a patent application in 2008.  The potentially life-saving treatment remains in the experimental stages.  However, the novel antibody treatment got a boost last week when Branty and Writebol became infected with Ebola.  The dire conditions of Dr. Kent Brantly and Nancy Writebol led to the use of the still experimental patented technology.

While the treatment remains experimental and more testing is required before the cocktail of antibodies will be approved for treatment of Ebola, the tragedy of the outbreak and Brantly and Writebol becoming infected themselves has fast-tracked this treatment for Ebola and may result in similar antibody therapies to treat other infection diseases.

Sources:
Ebola Vaccine Antibodies Are Made in Tobacco Plants
Ebola vaccine pioneer joked about use of genetically engineered virus to cull human population

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